If your lead's name sounds like either a romance novel heroine or a porn star the script will lose a point with me.
I'd love to say I bear no malice aforethought to characters like Dusty Boner or Lily McSweetness, but I'd be lying. Unless you're going for an over-the-top angle like a character on Pushing Daisies, then it's fun.
Otherwise, leave it for The Pie Maker.